Investigation of the spatiotemporal responses of nanoparticles in tumor tissues with a small-scale mathematical model.

The transport and accumulation of anticancer nanodrugs in tumor tissues are affected by many factors including particle properties, vascular density and leakiness, and interstitial diffusivity. It is important to understand the effects of these factors on the detailed drug distribution in the entire...

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Bibliographic Details
Main Authors: Cheng-Ying Chou, Chih-Kang Huang, Kuo-Wei Lu, Tzyy-Leng Horng, Win-Li Lin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3615073?pdf=render