Differential effect of actomyosin relaxation on the dynamic properties of focal adhesion proteins.

Treatment of cultured cells with inhibitors of actomyosin contractility induces rapid deterioration of stress fibers, and disassembly of the associated focal adhesions (FAs). In this study, we show that treatment with the Rho kinase inhibitor Y-27632, which blocks actomyosin contractility, induces d...

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Bibliographic Details
Main Authors: Irena Lavelin, Haguy Wolfenson, Israel Patla, Yoav I Henis, Ohad Medalia, Tova Volberg, Ariel Livne, Zvi Kam, Benjamin Geiger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3767655?pdf=render