An ω-3, but Not an ω-6 Polyunsaturated Fatty Acid Decreases Membrane Dipole Potential and Stimulates Endo-Lysosomal Escape of Penetratin

An ω-3, but Not an ω-6 Polyunsaturated Fatty Acid Decreases Membrane Dipole Potential and Stimulates Endo-Lysosomal Escape of Penetratin

Although the largely positive intramembrane dipole potential (DP) may substantially influence the function of transmembrane proteins, its investigation is deeply hampered by the lack of measurement techniques suitable for high-throughput examination of living cells. Here, we describe a novel emissio...

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Bibliographic Details
Main Authors: Florina Zakany, Mate Szabo, Gyula Batta, Levente Kárpáti, István M. Mándity, Péter Fülöp, Zoltan Varga, Gyorgy Panyi, Peter Nagy, Tamas Kovacs
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
membrane dipole potential
polyunsaturated fatty acids
cholesterol
penetratin
flow cytometry
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.647300/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.647300/full

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