Multiplexed drug-based selection and counterselection genetic manipulations in Drosophila

Multiplexed drug-based selection and counterselection genetic manipulations in Drosophila

Summary: The power of Drosophila melanogaster as a model system relies on tractable germline genetic manipulations. Despite Drosophila’s expansive genetics toolbox, such manipulations are still accomplished one change at a time and depend predominantly on phenotypic screening. We describe a drug-bas...

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Bibliographic Details
Main Authors: Nick Matinyan, Mansi S. Karkhanis, Yezabel Gonzalez, Antrix Jain, Alexander Saltzman, Anna Malovannaya, Alejandro Sarrion-Perdigones, Herman A. Dierick, Koen J.T. Venken
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
Drosophila melanogaster
model systems
genetics
screening
selection
counterselection
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721011475

Internet

http://www.sciencedirect.com/science/article/pii/S2211124721011475

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