Involvement of the cytokine MIF in the snail host immune response to the parasite Schistosoma mansoni.

We have identified and characterized a Macrophage Migration Inhibitory Factor (MIF) family member in the Lophotrochozoan invertebrate, Biomphalaria glabrata, the snail intermediate host of the human blood fluke Schistosoma mansoni. In mammals, MIF is a widely expressed pleiotropic cytokine with pote...

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Bibliographic Details
Main Authors: Alvaro Baeza Garcia, Raymond J Pierce, Benjamin Gourbal, Elisabeth Werkmeister, Dominique Colinet, Jean-Marc Reichhart, Colette Dissous, Christine Coustau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-09-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC2944803?pdf=render