Three-dimensional in vitro cancer spheroid models for Photodynamic Therapy: Strengths and Opportunities

Three dimensional, in vitro spheroid cultures offer considerable utility for the development and testing of anticancer photodynamic therapy regimens. More complex than monolayer cultures, three-dimensional spheroid systems replicate many of the important cell-cell and cell-matrix interactions that m...

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Bibliographic Details
Main Author: Conor L Evans
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Physics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphy.2015.00015/full