The reverse transcription inhibitor abacavir shows anticancer activity in prostate cancer cell lines.

BACKGROUND: Transposable Elements (TEs) comprise nearly 45% of the entire genome and are part of sophisticated regulatory network systems that control developmental processes in normal and pathological conditions. The retroviral/retrotransposon gene machinery consists mainly of Long Interspersed Nuc...

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Main Authors: Francesca Carlini, Barbara Ridolfi, Agnese Molinari, Chiara Parisi, Giuseppina Bozzuto, Laura Toccacieli, Giuseppe Formisano, Daniela De Orsi, Silvia Paradisi, Olì Maria Victoria Grober, Maria Ravo, Alessandro Weisz, Romano Arcieri, Stefano Vella, Simona Gaudi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2997057?pdf=render