Role of chymase in cigarette smoke-induced pulmonary artery remodeling and pulmonary hypertension in hamsters

<p>Abstract</p> <p>Background</p> <p>Cigarette smoking is an important risk factor for pulmonary arterial hypertension (PAH) in chronic obstructive pulmonary disease (COPD). Chymase has been shown to function in the enzymatic production of angiotensin II (AngII) and the...

Full description

Bibliographic Details
Main Authors: Yang Ting, Xu Dan, An Jin, He Guang-Ming, Chen Ya-Juan, Chen Lei, Ning Yun-Ye, Zhang Shang-Fu, Han Su-Xia, Wang Tao, Zhang Xiao-Hong, Wen Fu-Qiang
Format: Article
Language:English
Published: BMC 2010-03-01
Series:Respiratory Research
Online Access:http://respiratory-research.com/content/11/1/36