A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII
<p>Abstract</p> <p>Background</p> <p>Mutations of the epidermal growth factor receptor (EGFR) are a possible molecular target for cancer therapy. EGFR is frequently amplified in glioblastomas and 30 to 40% of glioblastomas also express the deletion mutation EGFRvIII. Th...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2007-04-01
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| Series: | Molecular Cancer |
| Online Access: | http://www.molecular-cancer.com/content/6/1/30 |