Maternal Diabetes Alters Expression of MicroRNAs that Regulate Genes Critical for Neural Tube Development

Maternal diabetes is known to cause neural tube defects (NTDs) in embryos and neuropsychological deficits in infants. Several metabolic pathways and a plethora of genes have been identified to be deregulated in developing brain of embryos by maternal diabetes, although the exact mechanism remains un...

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Bibliographic Details
Main Authors: Seshadri Ramya, Sukanya Shyamasundar, Boon Huat Bay, S. Thameem Dheen
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fnmol.2017.00237/full