Loss of wwox expression in zebrafish embryos causes edema and alters Ca2+ dynamics

We investigated the role of the WW domain-containing oxidoreductase (wwox) gene in the embryonic development of zebrafish, with particular emphasis on intracellular Ca2+ dynamics because Ca2+ is an important intracellular messenger. Comparisons between zebrafish wwox and human WWOX sequences identif...

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Bibliographic Details
Main Authors: Yusuke Tsuruwaka, Masataka Konishi, Eriko Shimada
Format: Article
Language:English
Published: PeerJ Inc. 2015-01-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/727.pdf