Biotinylated Surfome Profiling Identifies Potential Biomarkers for Diagnosis and Therapy of Aspergillus fumigatus Infection

Biotinylated Surfome Profiling Identifies Potential Biomarkers for Diagnosis and Therapy of Aspergillus fumigatus Infection

Aspergillus fumigatus is the most important airborne human-pathogenic mold, capable of causing both life-threatening invasive pulmonary aspergillosis in immunocompromised patients and allergy-inducing infections in individuals with atopic allergy. Despite its obvious medical relevance, timely diagno...

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Bibliographic Details
Main Authors: Lei-Jie Jia, Thomas Krüger, Matthew G. Blango, Ferdinand von Eggeling, Olaf Kniemeyer, Axel A. Brakhage
Format: Article
Language:English
Published: American Society for Microbiology 2020-08-01
Series:mSphere
Subjects:
aspergillus fumigatus
surface biotinylation
surfome
lc-ms/ms
allergens
heat shock protein
protein chaperone
proteomics
spores
surface proteins
Online Access:https://doi.org/10.1128/mSphere.00535-20

Internet

https://doi.org/10.1128/mSphere.00535-20

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