Histone demethylase retinoblastoma binding protein 2 regulates the expression of -smooth muscle actin and vimentin in cirrhotic livers

Histone demethylase retinoblastoma binding protein 2 regulates the expression of -smooth muscle actin and vimentin in cirrhotic livers

Liver cirrhosis is one of the most common diseases of Chinese patients. Herein, we report the high expression of a newly identified histone 3 lysine 4 demethylase, retinoblastoma binding protein 2 (RBP2), and its role in liver cirrhosis in humans. The siRNA knockdown of RBP2 expression in hepatic st...

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Bibliographic Details
Main Authors: Q. Wang, L.X. Wang, J.P. Zeng, X.J. Liu, X.M. Liang, Y.B. Zhou
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-09-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
RBP2
Liver cirrhosis
Fibrosis
-SMA
Vimentin
HSC
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000900739&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000900739&lng=en&tlng=en

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