A PRRSV GP5-Mosaic vaccine: Protection of pigs from challenge and ex vivo detection of IFNγ responses against several genotype 2 strains.

A PRRSV GP5-Mosaic vaccine: Protection of pigs from challenge and ex vivo detection of IFNγ responses against several genotype 2 strains.

Porcine reproductive and respiratory syndrome virus (PRRSV), is a highly mutable RNA virus that affects swine worldwide and its control is very challenging due to its formidable heterogeneity in the field. In the present study, DNA vaccines constructed with PRRSV GP5-Mosaic sequences were complexed...

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Bibliographic Details
Main Authors: Junru Cui, Caitlin M O'Connell, Antonio Costa, Yan Pan, Joan A Smyth, Paulo H Verardi, Diane J Burgess, Herbert J Van Kruiningen, Antonio E Garmendia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0208801

Internet

https://doi.org/10.1371/journal.pone.0208801

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