Monocytic HLA-DR expression kinetics in septic shock patients with different pathogens, sites of infection and adverse outcomes

Abstract Background Decreased monocytic (m)HLA-DR expression is the most studied biomarker of sepsis-induced immunosuppression. To date, little is known about the relationship between sepsis characteristics, such as the site of infection, causative pathogen, or severity of disease, and mHLA-DR expre...

Full description

Bibliographic Details
Main Authors: Guus P. Leijte, Thomas Rimmelé, Matthijs Kox, Niklas Bruse, Céline Monard, Morgane Gossez, Guillaume Monneret, Peter Pickkers, Fabienne Venet
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Critical Care
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13054-020-2830-x