Predicting human nucleosome occupancy from primary sequence.

Nucleosomes are the fundamental repeating unit of chromatin and comprise the structural building blocks of the living eukaryotic genome. Micrococcal nuclease (MNase) has long been used to delineate nucleosomal organization. Microarray-based nucleosome mapping experiments in yeast chromatin have reve...

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Bibliographic Details
Main Authors: Shobhit Gupta, Jonathan Dennis, Robert E Thurman, Robert Kingston, John A Stamatoyannopoulos, William Stafford Noble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-08-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC2515632?pdf=render