Comparative Efficacies of Linezolid vs. Tedizolid in an Experimental Murine Model of Vancomycin-Resistant Enterococcal (VRE) Bacteremia

Tedizolid (TZD) is an oxazolidinone derivative which demonstrates bacteriostatic activity through inhibition of protein synthesis. We compared the efficacies of TZD and an earlier-generation oxazolidinone, linezolid (LZD), in an experimental murine model of bacteremia caused by two VRE strains (one...

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Bibliographic Details
Main Authors: Wessam Abdelhady, Nagendra N. Mishra
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Medicine
Subjects:
TZD
LZD
VRE
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2019.00031/full