A Simple Model to Study Tau Pathology
Tau proteins play a role in the stabilization of microtubules, but in pathological conditions, tauopathies, tau is modified by phosphorylation and can aggregate into aberrant aggregates. These aggregates could be toxic to cells, and different cell models have been used to test for compounds that mig...
Main Authors: | Alexander L. Houck, Félix Hernández, Jesús Ávila |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2016-01-01
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Series: | Journal of Experimental Neuroscience |
Online Access: | https://doi.org/10.4137/JEN.S25100 |
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