Sevoflurane postconditioning enhanced hippocampal neuron resistance to global cerebral ischemia induced by cardiac arrest in rats through PI3K/Akt survival pathway

The purpose of this current study is to evaluate whether improvement of mitochondrial dysfunction was involved in the therapeutic effect of sevoflurane postconditioning in global cerebral ischemia after cardiac arrest (CA) via the PI3K/Akt pathway. In the first experiment, animals were randomly divi...

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Bibliographic Details
Main Authors: Zhihua Wang, Zhi Ye, Guoqing Huang, Na Wang, E Wang, Qulian Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2016.00271/full