NF-κB as potential target in the treatment of melanoma

NF-κB as potential target in the treatment of melanoma

<p>Abstract</p> <p>The RAS/MAP kinase pathway has attracted attention because activating mutations of the BRAF serine/threonine kinase was described in over 50% of melanomas. Very recently, selective and potent BRAF inhibitors have been developed. Several other signal transduction...

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Bibliographic Details
Main Authors: Madonna Gabriele, Ullman Claudio, Gentilcore Giusy, Palmieri Giuseppe, Ascierto Paolo
Format: Article
Language:English
Published: BMC 2012-03-01
Series:Journal of Translational Medicine
Subjects:
NF-κB
Melanoma
NBD peptide
Bortezomib
Curcumin
Online Access:http://www.translational-medicine.com/content/10/1/53

Internet

http://www.translational-medicine.com/content/10/1/53

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