Galectin-3 Deficiency Facilitates TNF-α-Dependent Hepatocyte Death and Liver Inflammation in MCMV Infection

Galectin-3 Deficiency Facilitates TNF-α-Dependent Hepatocyte Death and Liver Inflammation in MCMV Infection

Galectin-3 (Gal-3) has a role in multiple inflammatory pathways. Various, opposite roles of Gal-3 in liver diseases have been described but there are no data about the role of Gal-3 in development of hepatitis induced with cytomegalovirus infection. In this study we aimed to clarify the role of Gal-...

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Bibliographic Details
Main Authors: Bojana Stojanovic, Jelena Milovanovic, Aleksandar Arsenijevic, Bojan Stojanovic, Ivana Strazic Geljic, Nebojsa Arsenijevic, Stipan Jonjic, Miodrag L. Lukic, Marija Milovanovic
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Microbiology
Subjects:
galectin-3
hepatitis
murine cytomegalovirus infection
TNF-α
hepatocyte death
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00185/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00185/full

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