Lipid and energy metabolism in Wilson disease

Copper accumulation and deficiency are reciprocally connected to lipid metabolism. In Wilson disease (WD), which is caused by a genetic loss of function of the copper-transporting P-type ATPase beta, copper accumulates mainly in the liver and lipid metabolism is dysregulated. The underlying mechanis...

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Bibliographic Details
Main Authors: Tagreed A. Mazi, Noreene M. Shibata, Valentina Medici
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-03-01
Series:Liver Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2542568420300040