Rat Strain and Housing Conditions Alter Oxidative Stress and Hormone Responses to Chronic Intermittent Hypoxia

Rat Strain and Housing Conditions Alter Oxidative Stress and Hormone Responses to Chronic Intermittent Hypoxia

Sleep apnea has been associated with elevated risk for metabolic, cognitive, and cardiovascular disorders. Further, the role of hypothalamic–pituitary–adrenal (HPA) activation in sleep apnea has been controversial in human studies. Chronic intermittent hypoxia (CIH) is a rodent model, which mimics t...

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Bibliographic Details
Main Authors: Brina Snyder, Phong Duong, Mavis Tenkorang, E. Nicole Wilson, Rebecca L. Cunningham
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Physiology
Subjects:
hypothalamic–pituitary–adrenal axis
reproducibility
oxidative stress
corticosterone
ACTH
hyperphosphorylated tau
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.01554/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2018.01554/full

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