Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1

Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1

Objective(s): To investigate the role of the microRNA-125a (miR-125a) and BAK1 in intervertebral disc degeneration (IDD). Materials and Methods: Degenerative lumbar nucleus pulposus (NP) tissues were obtained from 193 patients who underwent resection, and normal controls consisted of normal NP tissu...

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Bibliographic Details
Main Authors: Ping Liu, Feng Chang, Ting Zhang, Gang Gao, Chen Yu, Sheng-Qiang Ding, Gen-Le Zuo, Xin-Hu Huang
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2017-11-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Apoptosis
BAK1 protein
Intervertebral disc degeneration
MIRN125 microRNA
Nucleus pulposus
Online Access:http://ijbms.mums.ac.ir/article_9542_87024314525a168e7fb5540f3afabe80.pdf

Internet

http://ijbms.mums.ac.ir/article_9542_87024314525a168e7fb5540f3afabe80.pdf

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