Initial evaluation of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate (FSPG) PET/CT imaging in patients with head and neck cancer, colorectal cancer, or non-Hodgkin lymphoma

Initial evaluation of (4S)-4-(3-[18F]fluoropropyl)-l-glutamate (FSPG) PET/CT imaging in patients with head and neck cancer, colorectal cancer, or non-Hodgkin lymphoma

Abstract Purpose (4S)-4-(3-[18F]Fluoropropyl)-l-glutamic acid ([18F]FSPG) measures system xC − transporter activity and shows promise for oncologic imaging. We present data on tumor uptake of this radiopharmaceutical in human subjects with head and neck cancer (HNC), colorectal cancer (CRC), and non...

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Bibliographic Details
Main Authors: Sonya Y. Park, Camila Mosci, Meena Kumar, Mirwais Wardak, Norman Koglin, Santiago Bullich, Andre Mueller, Mathias Berndt, Andrew W. Stephens, Frederick T. Chin, Sanjiv S. Gambhir, Erik S. Mittra
Format: Article
Language:English
Published: SpringerOpen 2020-08-01
Series:EJNMMI Research
Subjects:
Glutamate
xC − transporter
[18F]FSPG
Positron emission tomography
PET/CT
Head and neck cancer
Online Access:http://link.springer.com/article/10.1186/s13550-020-00678-2

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http://link.springer.com/article/10.1186/s13550-020-00678-2

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