Metabolomic Study to Determine the Mechanism Underlying the Effects of <i>Sagittaria sagittifolia</i> Polysaccharide on Isoniazid- and Rifampicin-Induced Hepatotoxicity in Mice

Metabolomic Study to Determine the Mechanism Underlying the Effects of <i>Sagittaria sagittifolia</i> Polysaccharide on Isoniazid- and Rifampicin-Induced Hepatotoxicity in Mice

In this study, a non-targeted metabolic profiling method based on ultra-performance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS) was used to characterize the plasma metabolic profile associated with the protective effects of the <i>Sagittaria sagittifolia</i> polys...

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Bibliographic Details
Main Authors: Xiu-Hui Ke, Chun-Guo Wang, Wei-Zao Luo, Jing Wang, Bing Li, Jun-Ping Lv, Rui-Juan Dong, Dong-Yu Ge, Yue Han, Ya-Jie Yang, Re-Yila Tu-Erxun, Hong-Shuang Liu, Yi-Chen Wang, Yan Liao
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
ultra-performance liquid chromatography-high resolution mass spectrometry (UPLC-HRMS)
isoniazid
rifampicin
<i>Sagittaria sagittifolia</i> polysaccharide
liver injury
Online Access:https://www.mdpi.com/1420-3049/23/12/3087

Internet

https://www.mdpi.com/1420-3049/23/12/3087

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