Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India

Elevated expression of RUNX3 co-expressing with EZH2 in esophageal cancer patients from India

Abstract Background Runt related transcription factor3 (RUNX3) is considered as a tumor suppressor gene (TSG) that functions through the TGF-β dependent apoptosis. Promoter methylation of the CpG islands of RUNX3 and overexpression of enhancer of zeste homolog 2 (EZH2) has been suggested to downregu...

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Bibliographic Details
Main Authors: Asad Ur Rehman, Mohammad Askandar Iqbal, Real Sumayya Abdul Sattar, Snigdha Saikia, Mohammad Kashif, Wasif Mohammad Ali, Subhash Medhi, Sundeep Singh Saluja, Syed Akhtar Husain
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Cancer Cell International
Subjects:
RUNX3
EZH2
Esophageal cancer
DNA methylation
Online Access:http://link.springer.com/article/10.1186/s12935-020-01534-y

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http://link.springer.com/article/10.1186/s12935-020-01534-y

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