Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential.

Epigenetic Alterations in Fanconi Anaemia: Role in Pathophysiology and Therapeutic Potential.

Fanconi anaemia (FA) is an inherited disorder characterized by chromosomal instability. The phenotype is variable, which raises the possibility that it may be affected by other factors, such as epigenetic modifications. These play an important role in oncogenesis and may be pharmacologically manipul...

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Bibliographic Details
Main Authors: Hélio Belo, Gabriela Silva, Bruno A Cardoso, Beatriz Porto, Jordi Minguillon, José Barbot, Jorge Coutinho, Jose A Casado, Manuela Benedito, Hema Saturnino, Emília Costa, Juan A Bueren, Jordi Surralles, Antonio Almeida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4605638?pdf=render

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http://europepmc.org/articles/PMC4605638?pdf=render

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