Quality Control and Nonclinical Research on CAR-T Cell Products: General Principles and Key Issues

Adoptive cell therapy using chimeric antigen receptor T (CAR-T) cells, which is a promising cancer immunotherapy strategy, has been developing very rapidly in recent years. CAR-T cells are genetically modified T cells that can specifically recognize tumor specific antigens on the surface of tumor ce...

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Bibliographic Details
Main Authors: Yonghong Li, Yan Huo, Lei Yu, Junzhi Wang
Format: Article
Language:English
Published: Elsevier 2019-02-01
Series:Engineering
Online Access:http://www.sciencedirect.com/science/article/pii/S2095809918308786