Desacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance

Objective: Regulation of energy balance depends on pro-opiomelanocortin (POMC)-derived peptides and melanocortin-4 receptor (MC4R). Alpha-melanocyte stimulating hormone (α-MSH) is the predicted natural POMC-derived peptide that regulates energy balance. Desacetyl-α-MSH, the precursor for α-MSH, is p...

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Bibliographic Details
Main Authors: Kathleen G. Mountjoy, Alexandre Caron, Kristina Hubbard, Avik Shome, Angus C. Grey, Bo Sun, Sarah Bould, Martin Middleditch, Beau Pontré, Ailsa McGregor, Paul W.R. Harris, Renata Kowalczyk, Margaret A. Brimble, Rikus Botha, Karen M.L. Tan, Sarah J. Piper, Christina Buchanan, Syann Lee, Anthony P. Coll, Joel K. Elmquist
Format: Article
Language:English
Published: Elsevier 2018-03-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817308190