Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.

Sensing and signaling of immunogenic extracellular RNAs restrain group 2 innate lymphoid cell-driven acute lung inflammation and airway hyperresponsiveness.

Repeated exposures to environmental allergens in susceptible individuals drive the development of type 2 inflammatory conditions such as asthma, which have been traditionally considered to be mainly mediated by Th2 cells. However, emerging evidence suggest that a new innate cell type, group 2 innate...

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Bibliographic Details
Main Authors: Li She, Hamad H Alanazi, Liping Yan, Edward G Brooks, Peter H Dube, Yan Xiang, Fushun Zhang, Yilun Sun, Yong Liu, Xin Zhang, Xiao-Dong Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0236744

Internet

https://doi.org/10.1371/journal.pone.0236744

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