LMNA cardiomyopathy: cell biology and genetics meet clinical medicine
Mutations in the LMNA gene, which encodes A-type nuclear lamins (intermediate filament proteins expressed in most differentiated somatic cells), cause a diverse range of diseases, called laminopathies, that selectively affect different tissues and organ systems. The most prevalent laminopathy is car...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2011-09-01
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Series: | Disease Models & Mechanisms |
Online Access: | http://dmm.biologists.org/content/4/5/562 |