LMNA cardiomyopathy: cell biology and genetics meet clinical medicine

Mutations in the LMNA gene, which encodes A-type nuclear lamins (intermediate filament proteins expressed in most differentiated somatic cells), cause a diverse range of diseases, called laminopathies, that selectively affect different tissues and organ systems. The most prevalent laminopathy is car...

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Bibliographic Details
Main Authors: Jonathan T. Lu, Antoine Muchir, Peter L. Nagy, Howard J. Worman
Format: Article
Language:English
Published: The Company of Biologists 2011-09-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/5/562