Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters

<p>Abstract</p> <p>Background</p> <p>The tumor suppressor gene <it>p53 (TP53) </it>controls numerous signaling pathways and is frequently mutated in human cancers. Novel p53 isoforms suggest alternative splicing as a regulatory feature of p53 activity.</p...

Full description

Bibliographic Details
Main Authors: Deppert Wolfgang, Lønning Per E, Geisler Stephanie B, Bergamaschi Anna, Langerød Anita, Myhre Simen, Baumbusch Lars O, Dornreiter Irene, Børresen-Dale Anne-Lise
Format: Article
Language:English
Published: BMC 2006-10-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/5/1/47