Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters
<p>Abstract</p> <p>Background</p> <p>The tumor suppressor gene <it>p53 (TP53) </it>controls numerous signaling pathways and is frequently mutated in human cancers. Novel p53 isoforms suggest alternative splicing as a regulatory feature of p53 activity.</p...
Main Authors: | , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2006-10-01
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Series: | Molecular Cancer |
Online Access: | http://www.molecular-cancer.com/content/5/1/47 |