Reverse-genetics studies of lncRNAs—what we have learnt and paths forward

Abstract Long non-coding RNAs (lncRNAs) represent a major fraction of the transcriptome in multicellular organisms. Although a handful of well-studied lncRNAs are broadly recognized as biologically meaningful, the fraction of such transcripts out of the entire collection of lncRNAs remains a subject...

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Bibliographic Details
Main Authors: Fan Gao, Ye Cai, Philipp Kapranov, Dongyang Xu
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Genome Biology
Online Access:http://link.springer.com/article/10.1186/s13059-020-01994-5