A Limited and Diverse Set of Suppressor Mutations Restore Function to INX-8 Mutant Hemichannels in the <i>Caenorhabditis elegans</i> Somatic Gonad
In <i>Caenorhabditis elegans</i>, gap junctions couple cells of the somatic gonad with the germline to support germ cell proliferation and gametogenesis. A strong loss-of-function mutation (T239I) affects the second extracellular loop (EL2) of the somatic INX-8 hemichannel subunit. These...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020-12-01
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| Series: | Biomolecules |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2218-273X/10/12/1655 |