Small compounds mimicking the adhesion molecule L1 improve recovery in a zebrafish demyelination model

Abstract Demyelination leads to a loss of neurons, which results in, among other consequences, a severe reduction in locomotor function, and underlies several diseases in humans including multiple sclerosis and polyneuropathies. Considerable clinical progress has been made in counteracting demyelina...

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Bibliographic Details
Main Authors: Suhyun Kim, Dong-Won Lee, Melitta Schachner, Hae-Chul Park
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-85412-1