Sidt2 regulates hepatocellular lipid metabolism through autophagy
SID1 transmembrane family member 2 (Sidt2) is an integral lysosomal membrane protein. To investigate its explicit function, we generated a global Sidt2 knockout mouse model (Sidt2−/−). Compared with the littermate controls, Sidt2−/− mice exhibited a remarkable accumulation of lipid droplets in liver...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2018-03-01
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| Series: | Journal of Lipid Research |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520331308 |