Molecular Subtype Conversion between Primary and Metastatic Breast Cancer Corresponding to the Dynamics of Apoptotic and Intact Circulating Tumor Cells

Molecular Subtype Conversion between Primary and Metastatic Breast Cancer Corresponding to the Dynamics of Apoptotic and Intact Circulating Tumor Cells

The presence of circulating tumor cells (CTCs), detected as a form of liquid biopsy is associated with poor survival in both early and metastatic breast cancer. Monitoring tumor biology based on intrinsic subtypes delivers treatment-relevant information on the heterogeneity or biomarker conversion b...

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Bibliographic Details
Main Authors: Stefan Stefanovic, Thomas M. Deutsch, Ralph Wirtz, Andreas Hartkopf, Peter Sinn, Florian Schuetz, Christof Sohn, Michael K. Bohlmann, Marc Sütterlin, Andreas Schneeweiss, Markus Wallwiener
Format: Article
Language:English
Published: MDPI AG 2019-03-01
Series:Cancers
Subjects:
breast cancer
intrinsic subtype
biomarker conversion
circulating tumor cells
RT-qPCR
Online Access:http://www.mdpi.com/2072-6694/11/3/342

Internet

http://www.mdpi.com/2072-6694/11/3/342

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