JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

Morphogens regulate growth and pattern in vertebrate and invertebrate limbs. Here, the authors show that the JAK/STAT pathway promotes the growth of the Hedgehog-producing cell population in theDrosophilawing, thereby allowing the stable localization of the BMP/Dpp organizer.

Bibliographic Details
Main Authors: Carles Recasens-Alvarez, Ana Ferreira, Marco Milán
Format: Article
Language:English
Published: Nature Publishing Group 2017-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms13815