Lithium promotes recovery of neurological function after spinal cord injury by inducing autophagy

Lithium promotes recovery of neurological function after spinal cord injury by inducing autophagy

Lithium promotes autophagy and has a neuroprotective effect on spinal cord injury (SCI); however, the underlying mechanisms remain unclear. Therefore, in this study, we investigated the effects of lithium and the autophagy inhibitor 3-methyladenine (3-MA) in a rat model of SCI. The rats were randoml...

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Bibliographic Details
Main Authors: Duo Zhang, Fang Wang, Xu Zhai, Xiao-Hui Li, Xi-Jing He
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; spinal cord injury; lithium; secondary injury; autophagy
diffusion tensor imaging; neuroprotection; functional recovery; immunohistochemistry; Beclin-1; light-chain 3B; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=12;spage=2191;epage=2199;aulast=Zhang

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=12;spage=2191;epage=2199;aulast=Zhang

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