Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation

Trim25 Is an RNA-Specific Activator of Lin28a/TuT4-Mediated Uridylation

RNA binding proteins have thousands of cellular RNA targets and often exhibit opposite or passive molecular functions. Lin28a is a conserved RNA binding protein involved in pluripotency and tumorigenesis that was previously shown to trigger TuT4-mediated pre-let-7 uridylation, inhibiting its process...

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Bibliographic Details
Main Authors: Nila Roy Choudhury, Jakub S. Nowak, Juan Zuo, Juri Rappsilber, Steven H. Spoel, Gracjan Michlewski
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124714008717

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http://www.sciencedirect.com/science/article/pii/S2211124714008717

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