Cellular connectomes as arbiters of local circuit models in the cerebral cortex

Large-scale connectomes from the mammalian brain are becoming available, but it remains unclear how informative these are for the distinction of circuit models. Here, the authors use connectome statistics to test competing models of local cortical circuits with approximate Bayesian computation.

Bibliographic Details
Main Authors: Emmanuel Klinger, Alessandro Motta, Carsten Marr, Fabian J. Theis, Moritz Helmstaedter
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22856-z