Age- and sex-dependent role of osteocytic pannexin1 on bone and muscle mass and strength

Age- and sex-dependent role of osteocytic pannexin1 on bone and muscle mass and strength

Abstract Pannexins (Panxs), glycoproteins that oligomerize to form hemichannels on the cell membrane, are topologically similar to connexins, but do not form cell-to-cell gap junction channels. There are 3 members of the family, 1–3, with Panx1 being the most abundant. All Panxs are expressed in bon...

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Bibliographic Details
Main Authors: Alexandra Aguilar-Perez, Rafael Pacheco-Costa, Emily G. Atkinson, Padmini Deosthale, Hannah M. Davis, Alyson L. Essex, Julian E. Dilley, Leland Gomez, Joseph E. Rupert, Teresa A. Zimmers, Roger J. Thompson, Matthew R. Allen, Lilian I. Plotkin
Format: Article
Language:English
Published: Nature Publishing Group 2019-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-50444-1

Internet

https://doi.org/10.1038/s41598-019-50444-1

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