ELISPOT Refinement Using Spot Morphology for Assessing Host Responses to Tuberculosis

Tuberculosis is a global health problem. The Mycobacterium bovis Bacille Calmette Guerin (BCG) vaccine has variable efficacy (0–80%) so there is a drive to develop novel vaccines. The cytokine, interferon gamma (IFNγ), is an essential component of the protective response to M. tuberculosis (M. tb) i...

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Bibliographic Details
Main Authors: Sally A. Sharpe, Philip D. Marsh, Ann Williams, Michael J. Dennis, Alice Marriott, Andrew D. White, Laura S. Sibley
Format: Article
Language:English
Published: MDPI AG 2012-03-01
Series:Cells
Subjects:
BCG
Online Access:http://www.mdpi.com/2073-4409/1/1/5