Microfluidic Biofabrication of 3D Multicellular Spheroids by Modulation of Non-geometrical Parameters

Microfluidic Biofabrication of 3D Multicellular Spheroids by Modulation of Non-geometrical Parameters

Three-dimensional (3D) cell spheroids are being increasingly applied in many research fields due to their enhanced biological functions as compared to conventional two-dimensional (2D) cultures. 3D cell spheroids can replicate tissue functions, which enables their use both as in vitro models and as...

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Bibliographic Details
Main Authors: Silvia Lopa, Francesco Piraino, Giuseppe Talò, Valerio Luca Mainardi, Simone Bersini, Margherita Pierro, Luigi Zagra, Marco Rasponi, Matteo Moretti
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
microfluidic
spheroid
3D culture
pellet culture
fluid dynamic
Online Access:https://www.frontiersin.org/article/10.3389/fbioe.2020.00366/full

Internet

https://www.frontiersin.org/article/10.3389/fbioe.2020.00366/full

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