Human mesenchymal stem cells protect human islets from pro-inflammatory cytokines.

Transplantation of human islets is an attractive alternative to daily insulin injections for patients with type 1 diabetes. However, the majority of islet recipients lose graft function within five years. Inflammation is a primary contributor to graft loss, and inhibiting pro-inflammatory cytokine a...

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Bibliographic Details
Main Authors: Telford Y Yeung, Karen L Seeberger, Tatsuya Kin, Adetola Adesida, Nadr Jomha, A M James Shapiro, Gregory S Korbutt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3364233?pdf=render