Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation

Transbuccal delivery of betahistine dihydrochloride from mucoadhesive tablets with a unidirectional drug flow: in vitro, ex vivo and in vivo evaluation

Mohamed A El-Nabarawi,1 Adel A Ali,2 Heba M Aboud,2 Amira H Hassan,2 Amany H Godah2 1Department of Pharmaceutics, Faculty of Pharmacy, Cairo University, Cairo, 2Department of Pharmaceutics, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, Egypt Objective: Betahistine dihydrochloride (BH.2HCl)...

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Bibliographic Details
Main Authors: El-Nabarawi MA, Ali AA, Aboud HM, Hassan AH, Godah AH
Format: Article
Language:English
Published: Dove Medical Press 2016-12-01
Series:Drug Design, Development and Therapy
Subjects:
Betahistine dihydrochloride
Transbuccal delivery
Unidirectional drug flow
Permeation enhancer
Relative bioavailability.
Online Access:https://www.dovepress.com/transbuccal-delivery-of-betahistine-dihydrochloride-from-mucoadhesive--peer-reviewed-article-DDDT

Internet

https://www.dovepress.com/transbuccal-delivery-of-betahistine-dihydrochloride-from-mucoadhesive--peer-reviewed-article-DDDT

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