AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study

AC Pulsed Field Ablation Is Feasible and Safe in Atrial and Ventricular Settings: A Proof-of-Concept Chronic Animal Study

IntroductionPulsed field ablation (PFA) exploits the delivery of short high-voltage shocks to induce cells death via irreversible electroporation. The therapy offers a potential paradigm shift for catheter ablation of cardiac arrhythmia. We designed an AC-burst generator and therapeutic strategy, ba...

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Bibliographic Details
Main Authors: Guido Caluori, Eva Odehnalova, Tomasz Jadczyk, Martin Pesl, Iveta Pavlova, Lucia Valikova, Steffen Holzinger, Veronika Novotna, Vladimir Rotrekl, Ales Hampl, Michal Crha, Dalibor Cervinka, Zdenek Starek
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
pulsed field ablation
irreversible electroporation (IRE)
radiofrequency ablation
atrial fibrillation
ventricular arrhythmia (VA)
preclinical cardiology
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2020.552357/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2020.552357/full

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