LPS induced inflammatory responses in human peripheral blood mononuclear cells is mediated through NOX4 and G<sub>i</sub>α dependent PI-3kinase signalling
<p>Abstract</p> <p>COPD is a disease of innate immunity and bacterial infections are a dominant cause of exacerbations in the later stages resulting in poor health and high mortality. The pathogen-associated molecular pattern (PAMP) lipopolysaccharide (LPS) is sensed by immune cell...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2012-01-01
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| Series: | Journal of Inflammation |
| Online Access: | http://www.journal-inflammation.com/content/9/1/1 |