Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017-10-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-017-01335-4 |
id |
doaj-972547f89abe41b0ab123373ee104007 |
---|---|
record_format |
Article |
spelling |
doaj-972547f89abe41b0ab123373ee1040072021-05-11T07:19:00ZengNature Publishing GroupNature Communications2041-17232017-10-018111310.1038/s41467-017-01335-4Functional mapping of brain synapses by the enriching activity-marker SynaptoZipMattia Ferro0Jacopo Lamanna1Maddalena Ripamonti2Gabriella Racchetti3Alessandro Arena4Sara Spadini5Giovanni Montesano6Riccardo Cortese7Vincenzo Zimarino8Antonio Malgaroli9Università Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleKeires AGNeurobiology of Learning Unit, Division of Neuroscience, Scientific Institute Ospedale San RaffaeleUniversità Vita-Salute San RaffaeleVisualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.https://doi.org/10.1038/s41467-017-01335-4 |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Mattia Ferro Jacopo Lamanna Maddalena Ripamonti Gabriella Racchetti Alessandro Arena Sara Spadini Giovanni Montesano Riccardo Cortese Vincenzo Zimarino Antonio Malgaroli |
spellingShingle |
Mattia Ferro Jacopo Lamanna Maddalena Ripamonti Gabriella Racchetti Alessandro Arena Sara Spadini Giovanni Montesano Riccardo Cortese Vincenzo Zimarino Antonio Malgaroli Functional mapping of brain synapses by the enriching activity-marker SynaptoZip Nature Communications |
author_facet |
Mattia Ferro Jacopo Lamanna Maddalena Ripamonti Gabriella Racchetti Alessandro Arena Sara Spadini Giovanni Montesano Riccardo Cortese Vincenzo Zimarino Antonio Malgaroli |
author_sort |
Mattia Ferro |
title |
Functional mapping of brain synapses by the enriching activity-marker SynaptoZip |
title_short |
Functional mapping of brain synapses by the enriching activity-marker SynaptoZip |
title_full |
Functional mapping of brain synapses by the enriching activity-marker SynaptoZip |
title_fullStr |
Functional mapping of brain synapses by the enriching activity-marker SynaptoZip |
title_full_unstemmed |
Functional mapping of brain synapses by the enriching activity-marker SynaptoZip |
title_sort |
functional mapping of brain synapses by the enriching activity-marker synaptozip |
publisher |
Nature Publishing Group |
series |
Nature Communications |
issn |
2041-1723 |
publishDate |
2017-10-01 |
description |
Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities. |
url |
https://doi.org/10.1038/s41467-017-01335-4 |
work_keys_str_mv |
AT mattiaferro functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT jacopolamanna functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT maddalenaripamonti functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT gabriellaracchetti functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT alessandroarena functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT saraspadini functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT giovannimontesano functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT riccardocortese functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT vincenzozimarino functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip AT antoniomalgaroli functionalmappingofbrainsynapsesbytheenrichingactivitymarkersynaptozip |
_version_ |
1721452491397136384 |