Functional mapping of brain synapses by the enriching activity-marker SynaptoZip

Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.

Bibliographic Details
Main Authors: Mattia Ferro, Jacopo Lamanna, Maddalena Ripamonti, Gabriella Racchetti, Alessandro Arena, Sara Spadini, Giovanni Montesano, Riccardo Cortese, Vincenzo Zimarino, Antonio Malgaroli
Format: Article
Language:English
Published: Nature Publishing Group 2017-10-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01335-4
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spelling doaj-972547f89abe41b0ab123373ee1040072021-05-11T07:19:00ZengNature Publishing GroupNature Communications2041-17232017-10-018111310.1038/s41467-017-01335-4Functional mapping of brain synapses by the enriching activity-marker SynaptoZipMattia Ferro0Jacopo Lamanna1Maddalena Ripamonti2Gabriella Racchetti3Alessandro Arena4Sara Spadini5Giovanni Montesano6Riccardo Cortese7Vincenzo Zimarino8Antonio Malgaroli9Università Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleUniversità Vita-Salute San RaffaeleKeires AGNeurobiology of Learning Unit, Division of Neuroscience, Scientific Institute Ospedale San RaffaeleUniversità Vita-Salute San RaffaeleVisualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.https://doi.org/10.1038/s41467-017-01335-4
collection DOAJ
language English
format Article
sources DOAJ
author Mattia Ferro
Jacopo Lamanna
Maddalena Ripamonti
Gabriella Racchetti
Alessandro Arena
Sara Spadini
Giovanni Montesano
Riccardo Cortese
Vincenzo Zimarino
Antonio Malgaroli
spellingShingle Mattia Ferro
Jacopo Lamanna
Maddalena Ripamonti
Gabriella Racchetti
Alessandro Arena
Sara Spadini
Giovanni Montesano
Riccardo Cortese
Vincenzo Zimarino
Antonio Malgaroli
Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
Nature Communications
author_facet Mattia Ferro
Jacopo Lamanna
Maddalena Ripamonti
Gabriella Racchetti
Alessandro Arena
Sara Spadini
Giovanni Montesano
Riccardo Cortese
Vincenzo Zimarino
Antonio Malgaroli
author_sort Mattia Ferro
title Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
title_short Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
title_full Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
title_fullStr Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
title_full_unstemmed Functional mapping of brain synapses by the enriching activity-marker SynaptoZip
title_sort functional mapping of brain synapses by the enriching activity-marker synaptozip
publisher Nature Publishing Group
series Nature Communications
issn 2041-1723
publishDate 2017-10-01
description Visualization of synaptic activity in the living brain is challenging. This study devises a simple and efficient scheme that reports synaptic vesicle recycling in vivo using SynaptoZip, a genetically encoded sensor of past synaptic activities.
url https://doi.org/10.1038/s41467-017-01335-4
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